Office address: Laboratory of Biotechnology
54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand
Tel: +66 25530 8555 (ext. 8558, 492830)
E-mail:

Research Scientist II

Research Experience (Specialties)
Gene regulation in pathogenic bacteria

Education
1989-1993 B.Sc. (Medical technology) Mahidol University, Bangkok
1993-1996 M.Sc. (Biotechnology) Mahidol University, Bangkok
1999-2003 Ph.D. (Microbiology) Cornell University, USA
2003-2004 Postdoctoral Training, Cornell University, USA

Publications
Methylation at position 32 of tRNA catalyzed by TrmJ alters oxidative stress response in Pseudomonas aeruginosa.
Jaroensuk J, Atichartpongkul S, Chionh YH, Wong YH, Liew CW, McBee ME, Thongdee N, Prestwich EG, DeMott MS, Mongkolsuk S, Dedon PC, Lescar J, Fuangthong M.
Nucleic Acids Res. 2016 Dec 15;44(22):10834-10848. Epub 2016 Sep 28.

Regulation of organic hydroperoxide stress response by two OhrR homologs in Pseudomonas aeruginosa.
Atichartpongkul S, Vattanaviboon P, Wisitkamol R, Jaroensuk J, Mongkolsuk S, Fuangthong M.
PLoS One. 2016 Aug 25;11(8):e0161982. doi: 10.1371/journal.pone.0161982. eCollection 2016.

IscR plays a role in oxidative stress resistance and pathogenicity of a plant pathogen,Xanthomonas campestris.
Fuangthong M, Jittawuttipoka T, Wisitkamol R, Romsang A, Duang-nkern J, Vattanaviboon P, Mongkolsuk S.
Microbiol Res. 2015 Jan;170:139-46. doi: 10.1016/j.micres.2014.08.004. Epub 2014 Aug 22.

Derepression of the Bacillus subtilis PerR peroxide stress response leads to iron deficiency.
Faulkner MJ, Ma Z, Fuangthong M, Helmann JD.
J Bacteriol. 2012 Mar;194(5):1226-35. doi: 10.1128/JB.06566-11. Epub 2011 Dec 22.

Exposure of Acinetobacter baylyi ADP1 to the biocide chlorhexidine leads to acquired resistance to the biocide itself and to oxidants.
Fuangthong M, Julotok M, Chintana W, Kuhn K, Rittiroongrad S, Vattanaviboon P, Mongkolsuk S.
J Antimicrob Chemother. 2011 Feb;66(2):319-22. doi: 10.1093/jac/dkq435. Epub 2010 Nov 23.

Mutations of ferric uptake regulator (fur) impair iron homeostasis, growth, oxidative stress survival, and virulence of Xanthomonas campestris pv. campestris.
Jittawuttipoka T, Sallabhan R, Vattanaviboon P, Fuangthong M, Mongkolsuk S.
Arch Microbiol. 2010 May;192(5):331-9. doi: 10.1007/s00203-010-0558-8. Epub 2010 Mar 17.

Analyses of the regulatory mechanism and physiological roles of Pseudomonas aeruginosa OhrR, a transcription regulator and a sensor of organic hydroperoxides.
Atichartpongkul S, Fuangthong M, Vattanaviboon P, Mongkolsuk S.
J Bacteriol. 2010 Apr;192(8):2093-101. doi: 10.1128/JB.01510-09. Epub 2010 Feb 5.

Mini-Tn7 vectors as genetic tools for gene cloning at a single copy number in an industrially important and phytopathogenic bacteria, Xanthomonas spp.
Jittawuttipoka T, Buranajitpakorn S, Fuangthong M, Schweizer HP, Vattanaviboon P, Mongkolsuk S.
FEMS Microbiol Lett. 2009 Sep;298(1):111-7. doi: 10.1111/j.1574-6968.2009.01707.x. Epub 2009 Jun 26.

Structural mechanism of organic hydroperoxide induction of the transcription regulator OhrR.
Newberry KJ, Fuangthong M, Panmanee W, Mongkolsuk S, Brennan RG.
Mol Cell. 2007 Nov 30;28(4):652-64.

The omlA gene is involved in multidrug resistance and its expression is inhibited by coumarins in Xanthomonas campestris pv. phaseoli.
Fuangthong M, Sallabhan R, Atichartpongkul S, Rangkadilok N, Sriprang R, Satayavivad J, Mongkolsuk S.
Arch Microbiol. 2008 Mar;189(3):211-8. Epub 2007 Oct 24.

Mutational analysis of active site residues essential for sensing of organic hydroperoxides by Bacillus subtilis OhrR.
Soonsanga S, Fuangthong M, Helmann JD.
J Bacteriol. 2007 Oct;189(19):7069-76. Epub 2007 Jul 27.

Structure of an OhrR-ohrA operator complex reveals the DNA binding mechanism of the MarR family.
Hong M, Fuangthong M, Helmann JD, Brennan RG.
Mol Cell. 2005 Oct 7;20(1):131-41.

Recognition of DNA by three ferric uptake regulator (Fur) homologs in Bacillus subtilis.
Fuangthong M, Helmann JD.
J Bacteriol. 2003 Nov;185(21):6348-57.

Use of a green fluorescent protein-based reporter fusion for detection of nitric oxide produced by denitrifiers.
Yin S, Fuangthong M, Laratta WP, Shapleigh JP.
Appl Environ Microbiol. 2003 Jul;69(7):3938-44.

Regulation of the Bacillus subtilis fur and perR genes by PerR: not all members of the PerR regulon are peroxide inducible.
Fuangthong M, Herbig AF, Bsat N, Helmann JD.
J Bacteriol. 2002 Jun;184(12):3276-86.

The repressor for an organic peroxide-inducible operon is uniquely regulated at multiple levels.
Mongkolsuk S, Panmanee W, Atichartpongkul S, Vattanaviboon P, Whangsuk W, Fuangthong M, Eiamphungporn W, Sukchawalit R, Utamapongchai S.
Mol Microbiol. 2002 May;44(3):793-802.

The OhrR repressor senses organic hydroperoxides by reversible formation of a cysteine-sulfenic acid derivative.
Fuangthong M, Helmann JD.
Proc Natl Acad Sci U S A. 2002 May 14;99(10):6690-5. Epub 2002 Apr 30.

OhrR is a repressor of ohrA, a key organic hydroperoxide resistance determinant in Bacillus subtilis.
Fuangthong M, Atichartpongkul S, Mongkolsuk S, Helmann JD.
J Bacteriol. 2001 Jul;183(14):4134-41.

A Xanthomonas alkyl hydroperoxide reductase subunit C (ahpC) mutant showed an altered peroxide stress response and complex regulation of the compensatory response of peroxide detoxification enzymes.
Mongkolsuk S, Whangsuk W, Vattanaviboon P, Loprasert S, Fuangthong M.
J Bacteriol. 2000 Dec;182(23):6845-9.

Molecular and physiological analysis of an OxyR-regulated ahpC promoter in Xanthomonas campestris pv. phaseoli.
Loprasert S, Fuangthong M, Whangsuk W, Atichartpongkul S, Mongkolsuk S.
Mol Microbiol. 2000 Sep;37(6):1504-14.

Mutations in oxyR resulting in peroxide resistance in Xanthomonas campestris.
Mongkolsuk S, Whangsuk W, Fuangthong M, Loprasert S.
J Bacteriol. 2000 Jul;182(13):3846-9.

Higher plants possess two structurally different poly(ADP-ribose) polymerases.
Babiychuk E, Cottrill PB, Storozhenko S, Fuangthong M, Chen Y, O’Farrell MK, Van Montagu M, Inzé D, Kushnir S.
Plant J. 1998 Sep;15(5):635-45.

Identification and characterization of a new organic hydroperoxide resistance (ohr) gene with a novel pattern of oxidative stress regulation from Xanthomonas campestris pv. phaseoli.
Mongkolsuk S, Praituan W, Loprasert S, Fuangthong M, Chamnongpol S.
J Bacteriol. 1998 May;180(10):2636-43.

Efficient gene tagging in Arabidopsis thaliana using a gene trap approach.
Babiychuk E, Fuangthong M, Van Montagu M, Inzé D, Kushnir S.
Proc Natl Acad Sci U S A. 1997 Nov 11;94(23):12722-7.

Isolation and characterization of a multiple peroxide resistant mutant from Xanthomonas campestris pv. phaseoli.
Fuangthong M, Mongkolsuk S.
FEMS Microbiol Lett. 1997 Jul 1;152(1):189-94.

Characterization of transcription organization and analysis of unique expression patterns of an alkyl hydroperoxide reductase C gene (ahpC) and the peroxide regulator operon ahpF-oxyR-orfX from Xanthomonas campestris pv. phaseoli.
Mongkolsuk S, Loprasert S, Whangsuk W, Fuangthong M, Atichartpongkun S.
J Bacteriol. 1997 Jun;179(12):3950-5.

Unusual growth phase and oxygen tension regulation of oxidative stress protection enzymes, catalase and superoxide dismutase, in the phytopathogen Xanthomonas oryzae pv. oryzae.
Chamnongpol S, Mongkolsuk S, Vattanaviboon P, Fuangthong M.
Appl Environ Microbiol. 1995 Jan;61(1):393-6.