Office address: Laboratory of Pharmacology, 4 ^th Floor, Biomedical Science Building
54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand
Tel: +66 2553 8555 (ext. 8290 )
E-mail:

Position: Research Scientist

Research Interests
My research focus is on neurobiology study of affecting brain cells both in vitro and in vivo upon the progression of neurodegenerative diseases in particular. I also experienced in development of novel non-viral/antibody based technology for drug and gene delivery into the brain. At Chulabhorn Research Institute, my main research aim is to investigate neuroprotective effects of Thai medicinal plants on acute and chronic brain disorders. Long-term damage of brain cells would possibly lead to the development of neurodegenerative diseases such as stroke, Alzheimer’s and Parkinson’s diseases. An expected outcome to pursue this aim is for the further development of alternative therapy of active compounds deriving from readily available Thai plants.

Education
• Doctor of Philosophy; Flinders University, Adelaide, South Australia (July 2008 – December 2011)
• Master of Biotechnology Studies, upgraded to Ph.D program; Flinders University, Adelaide, South Australia (July 2006 – July 2008)
• Bachelor of Science (Biotechnology); Mahidol University, Bangkok, Thailand (June 2002 – July 2006)

Area of expertise
MODEL SYSTEMS : Primary cell cultures, cell lines, animal model
IMMUNOLOGICAL BASED TECHNIQUES: Immunohistochemistry, receptor mediated gene delivery, antibody production
MOLECULAR BIOLOGY TECHNIQUES: Technique involving in genetically modification of DNA and RNA, Mammalian cells transfection
PROTEIN BASED TECHNIQUES: Protein analyses, extraction and purification using Column Chromatography (FPLC) and protein G column.
FLUORESCENT IMAGING TECHNIQUES: Live cell imaging, Fluorescent Recovery After Photo Bleaching (FRAP) assay, Confocal and fluorescence microscopy

Publications

• Glyphosate induces growth of estrogen receptor alpha positive cholangiocarcinoma cells via non-genomic estrogen receptor/ERK1/2 signaling pathway
  Sritana N, Suriyo T, Kanitwithayanun J, Songvasin BH, Thiantanawat A, Satayavivad J.
  Food Chem Toxicol. 2018; 118: 595-607.
• Insulin attenuates arsenic-induced neurite outgrowth impairments by activating the PI3K/Akt/SIRT1 signaling pathway.
  Niyomchan A, Watcharasit P, Visitnonthachai D, Homkajorn B, Thiantanawat A, Satayavivad J.
  Toxicol Lett. 2015; 236(3):138-44.
• Connexin 43 regulates astrocytic migration and proliferation in response to injury.
  Homkajorn B, Sims NR, Muyderman H.
  Neurosci Lett. 2010; 486(3):197-201.
• Astrocytic responses to DNA delivery using nucleofection.
  Muyderman H, Yew WP, Homkajorn B, Sims NR.
  Neurochem Res. 2010: 35(11):1771-9.