Name: Dr. Jutatip Boonsombat

Office address: R514B, R603 Natural Product Laboratory, Chemistry Research Building
54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand

Tel: +66 25530 8555 (ext. 8974 or 8803 )

E-mail: Research Scientist

Research Interests
Heterocyclic chemistry, total synthesis of natural product

Education
2003-2008 Ph.D. Organic Chemistry Emory University, Atlanta, GA, USA
1999-2002 M.S. Organic Chemistry Chulalongkorn University, Bangkok, Thailand
1996-1999 B.S. Chemistry Chulalongkorn University, Bangkok, Thailand

Work Experiences
2008 – present Researcher, Laboratory of Natural Products, Chulabhorn Research Institute
July-August 2009 Visiting researcher, Nagyoya University, Japan, JSPS- NRCT Core University Program
2003 – 2007 Teaching Assistant, Emory University, Atlanta, GA, USA
2002 – 2003 Research Assistant, Chulabhorn Research Institute
2002 Teaching Assistant, Ramkhamhaeng University, Thailand

Awards
2013 DPST award as the benefit of society
1999 Distinction with Second Class Honor, Chulalongkorn University, Bangkok, Thailand
1989 – 2002 Scholarship from The Development and Promotion of Science and Technology Talents Project (DPST), Thailand

Publications

1.Boonsombat, J.; Chawengrum, P.; Mahidol, C.; Kittakoop, P.; Ruchirawat, S.; Thongnest, S. A new 22,26-seco physalin steroid from Physalis angulata. 2018. Nat. Prod. Res. DOI: 10.1080/14786419.2018.1550766. in press.
2. Chawengrum, P., Boonsombat, J., Kittakoop, P., Mahidol, C., Ruchirawat, S., Thongnest, S., Cytotoxic and antimicrobial labdane and clerodane diterpenoids from Kaempferia elegans and Kaempferia pulchra, Phytochem. Lett., 2018, 24, 140–144.
3. Boonsombat, J., Mahidol, C., Chawengrum, P., Reuk-Ngam, N., Chimnoi, N., Techasakul, S., Ruchirawat, S., Thongnest, S., Roscotanes and Roscoranes: Oxygenated Abietane and Pimarane diterpenoids from Kaempferia roscoeana, Phytochemistry, 2017, 143, 36–44.
4. Boonsombat, J., Prachyawarakorn, V., Pansanit, A., Mahidol, C., Ruchirawat, S., Thongnest, S., Superbanone, A New 2-Aryl-3-Benzofuranone and Other Bioactive Constituents from the Tube Roots of Butea superba, Chem. Biodivers., 2017, DOI:10.1002/cbdv.201700044.
5. Thongnest, S., Boonsombat, J., Prawat, H., Mahidol, C., Ruchirawat, S., Ailanthusins A-G and nor-Lupane Triterpenoids from Ailanthus triphysa, Phytochemistry, 2017, 134, 98–105.
6. Bensulong, S.; Boonsombat, J.; Ruchirawat, S. DBU-mediated regioselective intramolecular cyclization/dehydration of ortho diketo phenoxyethers: A synthesis of 2,3-substituted g-benzopyranones Tetrahedron, 2013, 69, 9335.
7. Nakazaki A.; Huang W.-Y.; Koga K.; Yingyongnarongkul B.-E.; Boonsombat, J.; Sawayama Y.; Tsujimoto T.; Nishikawa T. Structural study on a naturally occurring terphenyl quinone Bioscience, biotechnology, and biochemistry, 2013, 77, 1529.
8. Boonsombat, J.; Padwa, A. An IMDAF cycloaddition approach toward the synthesis of the Lycopodium alkaloid (±)-fawcettidine. J. Org. Chem. 2011, 76, 2753.
9. France, S.; Boonsombat, J.; Leverett, C. A.; Padwa, A. Cycloaddition across the benzofuran rings as an approach to the morphine alkaloids. J. Org. Chem. 2008, 73, 8120.
10. Boonsombat, J.; Zhang, H.; Chughtai, M. J.; Hartung, J.; Padwa, A. A general synthetic entry to the pentacyclic Strychnos alkaloid family, using a [4 + 2]-cycloaddition/rearrangement cascade sequence. J. Org. Chem. 2008, 73, 3539.
11. Padwa, A.; Chughtai, M. J.; Boonsombat, J.; Rashatasakhon, P. A Rh(II)-catalyzed cycloaddition approach toward the synthesis of komaroviquinone. Tetrahedron 2008, 64, 4758.
12. Bates, R. W.; Boonsombat, J.; Lu, Y.; Nemeth, J. A.; Sa-Ei, K.; Song, P.; Cai, M. P.; Cranwell, P. B.; Winbush, S. N,O-Heterocycles as synthetic intermediates. Pure Appl. Chem. 2008, 80, 681.
13. Padwa, A.; Boonsombat, J.; Rashatasakhon, P. An approach toward oxidopyrylium ylides using Rh(II)-catalyzed cyclization chemistry. Tetrahedron Lett. 2007, 48, 5938.
14. Zhang, H.; Boonsombat, J.; Padwa, A. Total synthesis of (±)-strychnine via a [4 + 2]-cycloaddition/
rearrangement cascade. Org. Lett. 2007, 9, 279.
15. Padwa, A.; Boonsombat, J.; Rashatasakhon, P.; Willis, J. Efficient construction of the oxatricyclo [6.3.1.00,0]dodecane core of komaroviquinone using a cyclization/cycloaddition cascade of a rhodium carbenoid intermediate. Org. Lett. 2005, 7, 3725.
16. Bates, R. W.; Boonsombat, J. Synthesis of (+)-sedamine by tethered cyclofunctionalisation.
Org. Biomol. Chem. 2005, 3, 520.
17. Plemper, R. K.; Erlandson, K. J.; Lakdawala, A. S.; Sun, A.; Prussia, A.; Boonsombat, J.; Aki-Sener, E.; Yalcin, I.; Yildiz, I.; Temiz-Arpaci, O.; Tekiner, B.; Liotta, D. C.; Snyder, J. P.; Compans, R. W. A target site for template-based design of measles virus entry inhibitors. Proc. Natl. Acad. Sci. USA 2004, 101, 5628.
18. Bates, R. W.; Boonsombat, J. The pyridinium reduction route to alkaloids: a synthesis of (±)-tashiromine. J. Chem. Soc., Perkin Trans.1 2001, 7, 654.