Detection of environmental toxicants by dielectrophoresis

Detection of environmental toxicants by dielectrophoresis

Dielectrophoresis (DEP) applies the principles of both biology and physics in detection of low levels of pollutants arising from industrial and agricultural sources in the water supply. DEP is the motion of particles induced by non-uniform, oscillating electrical fields. More »

Impact of industrial chemicals on the environment an health of workers and population in industrial communities

Impact of industrial chemicals on the environment an health of workers and population in industrial communities

To address long-term health concerns and improve the quality of life of industrial workers and communities living in industrial areas, a project has been set up to study the impacts on the environment of potentially toxic chemicals in petrochemical industries or gasoline service attendants with regarding to their chronic effect on the health of workers and on people living near industrial areas. More »

Impacts of exposure to genotoxic air pollutants in susceptible populations

Impacts of exposure to genotoxic air pollutants in susceptible populations

Genotoxic air pollutants have significant potential impacts on human health. Polycyclic aromatic hydrocarbons (PAHs) have been associated with lung cancer, while volatile organic compounds (VOCs), such as benzene and 1,3-butadiene, have been associated with leukemia incidence. More »

Health impacts of arsenic: studies on gene expression

Health impacts of arsenic: studies on gene expression

Arsenic is an environmental pollutant that has been classified as a human carcinogen by the International Agency for Research on Cancer (IARC). It is naturally found in the environment, and is used as a therapeutic agent in pigs and chickens, as well as a pesticide. More »

 


       Chemical pollution in the environment is a problem that impacts human health and development of disease in many countries around the world, including Thailand. The World Health Organization (WHO) has estimated that 24% of the global disease burden and an estimated 23% of all deaths are attributable to environmental factors, and that as many as 13 million deaths could be prevented every year by making our environment healthier. In terms of a specific disease of increasing concern around the world, WHO has estimated that roughly 19 percent of all cancers is attributable to the environment.

       Research in the area of environmental toxicology is important for sustainable development, as it allows us to identify key problem areas that need to be addressed in order to minimize impacts from the use of chemicals. This is an area of growing interest and concern, both to the scientific community and to the general public, since chemicals and pollutants together with other environmental factors are recognized as major determinants of human health status. An increasing number of publications indicate a clear impact of environmental pollutants on human health through modulation of physiological and pathological status.

       The Environmental Toxicology Laboratory at the Chulabhorn Research Institute therefore focuses on research into major environmental health problems from exposure to chemicals in the environment. Research is conducted that spans the exposure-disease paradigm, from measurement of ambient exposures to assessment of internal exposures and early biological effects that can be linked to disease development. Chemical pollutants of specific interest include carcinogenic compounds found in the environment and in food, as well as volatile organic compounds, pesticides, toxic metals, and other toxicants. Research that leads to identification of sources of exposure and assessment of mechanisms underlying development of early effects can lead to measures for prevention of disease for the ultimate benefit for human health.

 

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