Name: Dr. Jittiporn Chaisaingmongkol

Office address: Chemical Carcinogenesis Laboratory, Biomedical Building

54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand

Tel:  +66 25530 8555 (ext.8262)

E-mail:

Research Experience (Specialties):
– Cancer biology and molecular biology (Epigenetics and DNA repair)
– Integrated and functional genomics of human liver cancer (Hepatocellular carcinoma and cholangiocarcinoma)

Education
2000 – 2006 Diplom Degree (Bachelor and Master degree) Bayerischen Julius-Maximilians-Universitaet Wuerzburg, Wuerzburg, GERMANY
2006 – 2011 Doctor of Science (DR. RER. NAT.) Ruperto-Carola University of Heidelberg, Heidelberg, GERMANY

Awards
2017 Second Prize Oral presentation (Science and Medicine). Common molecular subtypes among Asian hepatocellular carcinoma and cholangiocarcinoma (Abstract# O2-2). International Conference on Innovation in Cancer Research and Care. 18-20 December 2017.

1998-2011 Received the Royal Thai Government Scholarship to study aboard

1998 Development and Promotion of Science and Technology Talent (DPST) project student, Faculty of Science, Chiang Mai University, THAILAND

Work Activities
2011 Postdoctoral Fellow at the German Cancer Research Center, Heidelberg, GERMANY

2013 – 2016 Visiting fellow at Laboratory of Human Carcinogenesis, National Cancer Institute, National Institute of Health, Bethesda, MD, USA

2011 – Present Researcher at Laboratory of Chemical Carcinogenesis, Chulabhorn Research Institute, Bangkok, THAILAND

Publications
Chaisaingmongkol  J, Budhu A, Dang H, Rabibhadana S, Pupacdi B, Kwon S, Forgues M, Pomyen Y, Bhudhisawasdi V, Lertprasertsuke N, Chotirosniramit A, Pairojkul C, Auewarakul C, Sricharunrat T, Phornphutkul K, Sangrajrang S, Cam M, He P, Hewitt S, Ylaya K, Wu X, Andersen J, Thorgeirsson S, Waterfall J, Zhu Y, Walling J, Stevenson H, Edelman D, Meltzer P, Loffredo C, Hama N, Shibata T, Wiltrout R, Harris C, Mahidol C, Ruchirawat M, Wang X. Molecular subtypes among Asian cholangiocarcinoma. The 2nd Asia Pacific Cholangiocarcinoma Conference 2018, Bangkok, Thailand (23-24 March 2018) as Invited speaker

Budhu A, Pomyen Y,  Chaisaingmongkol  J, Dang H , Rabibhadana S , Pupacdi B, Forgues F, Bhudhisawasdi V, Lertprasertsuke N, Chotirosniramit A, Pairojkul C, Auewarakul CU, Sricharunrat T, Phornphutkul K, Sangrajrang S, Mahidol C, Ruchirawat M, Wang XW. Abstract #ABSSUB-250 Global Tissue And Serum Metabolomics Reveals Altered Tumor Biochemical Activity In Molecular Subtypes Of Hepatocellular Carcinoma And Cholangiocarcinoma. International Liver Cancer Association 11th Annual Conference Seoul, South Korea (15 – 17 September 2017).

Chaisaingmongkol J, Budhu A, Dang H, Rabibhadana R, Pupacdi B, Kwon SM, Forgues M, Pomyen Y, Bhudhisawasdi V, Lertprasertsuke N, Chotirosniramit A, Pairojkul C, Auewarakul C, Sricharunrat T, Phornphutkul K, Sangrajrang S, Cam M, He P, Hewitt SM, Wu X, Andersen J, Thorgeirsson SS, Waterfall JJ,  Zhu YJ,  Walling J, Stevenson HS, Edelman D, Meltzer PS, Loffredo CA, Hama N, Shibata T, Wiltrout RH, Harris CC, Mahidol C, Ruchirawat M, Wang XW; on behalf of the TIGER-LC Consortium, Race/Ethnicity-related Common Molecular Subtypes among Asian Cholangiocarcinoma and Hepatocellular Carcinoma Identified by Integrated Genomics, Cancer Cell, doi: 10.1016/j.ccell.2017.05.009. Epub 2017 June 22.

Weigel C,  Chaisaingmongkol J,  Kuhmann C,  Santi I,  Winkler V, Bogatyrova O, Justo L. Bermejo JL,  Chan TL, Lasitschka F, Bohrer MH, Marx A, Autschbach F, von Haußen RH, Dyckhoff G, Delank KW, Hoermann K, Lippert BM, Baier G,  Dietz A,  Oakes CC,  Plass C, Becher H,  Schmezer P,  Ramroth H,  Popanda O.  Abstract # 3364: DNA methylation loss at an enhancer site of the DNA repair gene TREX2 is an epigenetic feature in multiple cancers. American Association for Cancer Research (AACR) Annual Meeting 2017, Washington DC, USA (April 1-5, 2017).

Budhu A, Chaisaingmongkol J, Dang H, Rabibhadana S, Pupacdi B,  Kwon SM, Forgues M, Pomyen Y, Bhudhisawasdi V, Lertprasertsuke N, Chotirosniramit A, Pairojkul C, Auewarakul C, Sricharunrat T, Phornphutkul K, Sangrajrang S, Cam M, He P,  Hewitt SM, Wu X, Thorgeirsson S, Waterfall JJ, Zhu YJ, Walling J, Stevenson HS, Edelman D, Meltzer PS, Loffredo CA, Wiltrout RH, Harris C, Mahidol C, Ruchirawat M, Wang XW.  Abstract #4390 The Thailand initiative in genomics and expression research in liver cancer: Race related common molecular subtypes among Asian hepatocellular carcinoma and cholangiocarcinoma identifıed by integrated genomics. . American Association for Cancer Research (AACR) Annual Meeting 2017, Washington DC, USA (April 1-5, 2017).

Haznadar M, Krausz KW,  Diehl CM, Bowman ED, Budhu A, Chaisaingmongkol J, Rabibhadana S, Forgues M,  Oike T, Ruchirawat M, Gonzalez FJ, Wang XW, Harris C. Abstract #2500 Urinary metabolites are diagnostic biomarkers of liver cancer. American Association for Cancer Research (AACR) Annual Meeting 2017, Washington DC, USA (April 1-5, 2017).

Budhu A, Chaisaingmongkol J, Dang H, Rabibhadana S, Pupacdi B, Kwon S,  Forgues M, Bhudhisawasdi V, Lertprasertsuke N, Chotirosniramit A, Pairojkul C, Auewarakul C, Sricharunrat T, Phornphutkul K,  Sangrajrang S, Cam M, He P, Hewitt S, Wu X, Thorgeirsson S, Meltzer P, Loffredo C, Wiltrout W, Harris C,  Mahidol C, Ruchirawat M, Wang X:  The Thailand Initiative in Genomics and Expression Research for Liver Cancer (TIGER-LC): Race/ Ethnicity-Related Common Molecular Subtypes among Asian Hepatocellular Carcinoma and Cholangiocarcinoma Identified by Integrated Genomics.  International Liver Cancer Association 10th Annual Conference Vancouver, Canada (9 – 11 September 2016).

Budhu A, Chaisaingmongkol J, Dang H, Kwan SM, Rabibhadana R, Pupacdi B, Forgues M, Bhudhisawasdi V, Lertprasertsuke N, Chotirosniramit A, Pairojkul C, Auewarakul C, Sricharunrat T, Phornphutkul K, Sangrajrang S, Cam M, He P, Hewitt SM, Wu X, Thorgeirsson SS, Meltzer PS, Christopher Loffredo LA, Wiltrout RH, Harris CC, Mahidol C, Ruchirawat M, Wang XW: The Thailand initiative in genomics and expression research for liver cancer (TIGER-LC): Defining novel subtypes of hepatocellular carcinoma and cholangiocarcinoma by integrated genomics. International Liver Cancer Association  (ILCA)’s Annual Conferences, Paris, France (September 4-6,  2015)           .

Chaisaingmongkol J, Budhu A, Dang H, Rabibhadana R, Pupacdi B, Forgues M, Bhudhisawasdi V, Lertprasertsuke N, Chotirosniramit A, Pairojkul C, Auewarakul C, Sricharunrat T, Phornphutkul K, Sangrajrang S, Cam M, He P, Hewitt SM, Wu X, Thorgeirsson SS, Meltzer PS, Christopher Loffredo LA, Wiltrout RH, Harris CC, Mahidol C, Ruchirawat M, Wang XW: The Thailand initiative in genomics and expression research for liver cancer (TIGER-LC): Defining novel subtypes of hepatocellular carcinoma and cholangiocarcinoma.        American Association for Cancer Research (AACR) Annual Meeting 2015, Philadelphia, USA (April 18-22, 2015).

Scarzello A, Jiang Q, Back T, Dang H, Hodge D, Hanson C, Subleski J, Weiss J, Stauffer J, Chaisaingmongkol J, Rabibhadana S, Ruchirawat M, Ortaldo J, Wang X, Norris P, Ware C, Wiltrout R. 2015        LT β R signalling preferentially accelerates oncogenic AKT-initiated liver tumours. Gut 2015 Jul 23:1-11.

Warta R, Herold-Mende C, Chaisaingmongkol J, Popanda O, Mock A, Mogler C, Osswald F, Herpel E, Küstner S, Eckstein V, Plass C, Plinkert P, Schmezer P, Dyckhoff G. Reduced promoter methylation and increased expression of CSPG4 negatively influences survival of HNSCC patients. Int J Cancer. 2014 Dec 1;135(11):2727-34.

Campos B, Warta R, Chaisaingmongkol J, Geiselhart L, Popanda O, Hartmann C, von Deimling A, Unterberg A, Plass C, Schmezer P, Herold-Mende C: Epigenetically mediated downregulation of the differentiation-promoting chaperon protein CRABP2 in astrocytic gliomas. Int J Cancer. 2012 Oct 15;131(8):1963-8.

Chaisaingmongkol J, Popanda O, Warta R, Dyckhoff G, Herpel E, Geiselhart L, Claus R, Lasitschka F, Campos B, Oakes C, Bermejo JL, Herold-Mende C, Plass C, Schmezer P: Epigenetic screen of human DNA repair genes identifies aberrant promoter methylation of NEIL1 in head and neck squamous cell carcinoma. Oncogene. 2012 Jan 30.